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Direct Interaction of Nuclear Liver X Receptor-β with ABCA1 Modulates Cholesterol Efflux

Cholesterol is an essential component of eukaryotic cells; at the same time, however, hyperaccumulation of cholesterol is harmful. Therefore, the ABCA1 gene, the product of which mediates secretion of cholesterol, is highly regulated at both the transcriptional and post-transcriptional levels. The t...

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Main Authors: Hozoji, Masako, Munehira, Youichi, Ikeda, Yuika, Makishima, Makoto, Matsuo, Michinori, Kioka, Noriyuki, Ueda, Kazumitsu
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662070/
https://ncbi.nlm.nih.gov/pubmed/18782758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804599200
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