Inhibition of Glutathione Production Induces Macrophage CD36 Expression and Enhances Cellular-oxidized Low Density Lipoprotein (oxLDL) Uptake

The glutathione (GSH)-dependent antioxidant system has been demonstrated to inhibit atherosclerosis. Macrophage CD36 uptakes oxidized low density lipoprotein (oxLDL) thereby facilitating foam cell formation and development of atherosclerosis. It remains unknown if GSH can influence macrophage CD36 e...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Yang, Xiaoxiao, Yao, Hui, Chen, Yuanli, Sun, Lei, Li, Yan, Ma, Xingzhe, Duan, Shengzhong, Li, Xiaoju, Xiang, Rong, Han, Jihong, Duan, Yajun
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2015
Soggetti:
Lipids
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4571935/
https://ncbi.nlm.nih.gov/pubmed/26187465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.654582
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