Inhibition of Glutathione Production Induces Macrophage CD36 Expression and Enhances Cellular-oxidized Low Density Lipoprotein (oxLDL) Uptake

The glutathione (GSH)-dependent antioxidant system has been demonstrated to inhibit atherosclerosis. Macrophage CD36 uptakes oxidized low density lipoprotein (oxLDL) thereby facilitating foam cell formation and development of atherosclerosis. It remains unknown if GSH can influence macrophage CD36 e...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Yang, Xiaoxiao, Yao, Hui, Chen, Yuanli, Sun, Lei, Li, Yan, Ma, Xingzhe, Duan, Shengzhong, Li, Xiaoju, Xiang, Rong, Han, Jihong, Duan, Yajun
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Lipids
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4571935/
https://ncbi.nlm.nih.gov/pubmed/26187465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.654582
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