Implication of lipoprotein associated phospholipase A(2) activity in oxLDL uptake by macrophages

Recognition and uptake of oxidized LDL (oxLDL) by scavenger receptors of macrophages and foam cell formation are mediated by the oxidatively modified apolipoprotein B (ApoB) and lipid moiety of oxLDL. A great amount of oxidized phosphatidylcholine (oxPC) of oxLDL is hydrolyzed at the sn-2 position b...

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Detalhes bibliográficos
Main Authors: Markakis, Konstantinos P., Koropouli, Maria K., Grammenou-Savvoglou, Stavroula, van Winden, Ewoud C., Dimitriou, Andromaxi A., Demopoulos, Constantinos A., Tselepis, Alexandros D., Kotsifaki, Eleni E.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903815/
https://ncbi.nlm.nih.gov/pubmed/20332422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M003558
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