Phosphonopeptides as Antibacterial Agents: Alaphosphin and Related Phosphonopeptides

Alaphosphin, l-alanyl-l-1-aminoethylphosphonic acid, was selected from a range of phosphonopeptides for evaluation in humans on the basis of its antibacterial activity, pharmacokinetics, and stability to intestinal and kidney peptidases. In vitro, the antibacterial action was antagonized by small pe...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Allen, John G., Atherton, Frank R., Hall, Michael J., Hassall, Cedric H., Holmes, Simon W., Lambert, Robert W., Nisbet, Louis J., Ringrose, Peter S.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1979
Soggetti:	Pharmacology and Therapeutics
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352739/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/43113/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.15.5.684
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