Phosphonopeptides as Antibacterial Agents: Alaphosphin and Related Phosphonopeptides

Alaphosphin, l-alanyl-l-1-aminoethylphosphonic acid, was selected from a range of phosphonopeptides for evaluation in humans on the basis of its antibacterial activity, pharmacokinetics, and stability to intestinal and kidney peptidases. In vitro, the antibacterial action was antagonized by small pe...

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Bibliografiske detaljer
Main Authors: Allen, John G., Atherton, Frank R., Hall, Michael J., Hassall, Cedric H., Holmes, Simon W., Lambert, Robert W., Nisbet, Louis J., Ringrose, Peter S.
Format: Artigo
Sprog:Inglês
Udgivet: 1979
Fag:
Pharmacology and Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC352739/
https://ncbi.nlm.nih.gov/pubmed/43113
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