Phosphonopeptides as Antibacterial Agents: Alaphosphin and Related Phosphonopeptides

Alaphosphin, l-alanyl-l-1-aminoethylphosphonic acid, was selected from a range of phosphonopeptides for evaluation in humans on the basis of its antibacterial activity, pharmacokinetics, and stability to intestinal and kidney peptidases. In vitro, the antibacterial action was antagonized by small pe...

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Hlavní autoři: Allen, John G., Atherton, Frank R., Hall, Michael J., Hassall, Cedric H., Holmes, Simon W., Lambert, Robert W., Nisbet, Louis J., Ringrose, Peter S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 1979
Témata:
Pharmacology and Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC352739/
https://ncbi.nlm.nih.gov/pubmed/43113
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