Phosphonopeptides as Antibacterial Agents: Alaphosphin and Related Phosphonopeptides

Alaphosphin, l-alanyl-l-1-aminoethylphosphonic acid, was selected from a range of phosphonopeptides for evaluation in humans on the basis of its antibacterial activity, pharmacokinetics, and stability to intestinal and kidney peptidases. In vitro, the antibacterial action was antagonized by small pe...

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Autori principali: Allen, John G., Atherton, Frank R., Hall, Michael J., Hassall, Cedric H., Holmes, Simon W., Lambert, Robert W., Nisbet, Louis J., Ringrose, Peter S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1979
Soggetti:
Pharmacology and Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC352739/
https://ncbi.nlm.nih.gov/pubmed/43113
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