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Protonation State of a Conserved Acidic Amino Acid Involved in Na(+) Binding to the Glutamate Transporter EAAC1
[Image: see text] Substrate transport by glutamate transporters is coupled to the co-transport of 3 Na(+) ions and counter-transport of 1 K(+) ion. The highly conserved Asp454, which may be negatively charged, is of interest as its side chain may coordinate cations and/or contribute to charge compen...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Chemical
Society
2012
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| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3526966/ https://ncbi.nlm.nih.gov/pubmed/23259042 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn300163p |
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