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Two conformational changes are associated with glutamate translocation by the glutamate transporter EAAC1

Glutamate is transported across membranes by means of a carrier mechanism that is thought to require conformational changes of the transport protein. In this work, we have determined the thermodynamic parameters of glutamate and Na(+) binding steps to their extracellular binding sites along with the...

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Autori principali: Mim, Carsten, Tao, Zhen, Grewer, Christof
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430070/
https://ncbi.nlm.nih.gov/pubmed/17630698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi7005465
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