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Cooperation of the Conserved Aspartate 439 and Bound Amino Acid Substrate Is Important for High-Affinity Na(+) Binding to the Glutamate Transporter EAAC1

The neuronal glutamate transporter EAAC1 contains several conserved acidic amino acids in its transmembrane domain, which are possibly important in catalyzing transport and/or binding of co/countertransported cations. Here, we have studied the effects of neutralization by site-directed mutagenesis o...

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מידע ביבליוגרפי
Main Authors: Tao, Zhen, Grewer, Christof
פורמט: Artigo
שפה:Inglês
יצא לאור: The Rockefeller University Press 2007
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151618/
https://ncbi.nlm.nih.gov/pubmed/17389249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200609678
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