Disulfide Bond As a Switch for Copper-Zinc Superoxide Dismutase Activity in Asthma

AIM: Loss of superoxide dismutase (SOD) activity is a defining biochemical feature of asthma. However, mechanisms for the reduced activity are unknown. We hypothesized that loss of asthmatic SOD activity is due to greater susceptibility to oxidative inactivation. Result: Activity assays of blood sam...

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Main Authors: Ghosh, Sudakshina, Willard, Belinda, Comhair, Suzy A.A., Dibello, Patricia, Xu, Weiling, Shiva, Sruti, Aulak, Kulwant S., Kinter, Michael, Erzurum, Serpil C.
פורמט: Artigo
שפה:Inglês
יצא לאור: Mary Ann Liebert, Inc. 2013
נושאים:
Original Research Communications
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526896/
https://ncbi.nlm.nih.gov/pubmed/22867017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2012.4566
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