Insights into the Role of the Unusual Disulfide Bond in Copper-Zinc Superoxide Dismutase

The functional and structural significance of the intrasubunit disulfide bond in copper-zinc superoxide dismutase (SOD1) was studied by characterizing mutant forms of human SOD1 (hSOD) and yeast SOD1 lacking the disulfide bond. We determined x-ray crystal structures of metal-bound and metal-deficien...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Sea, Kevin, Sohn, Se Hui, Durazo, Armando, Sheng, Yuewei, Shaw, Bryan F., Cao, Xiaohang, Taylor, Alexander B., Whitson, Lisa J., Holloway, Stephen P., Hart, P. John, Cabelli, Diane E., Gralla, Edith Butler, Valentine, Joan Selverstone
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Enzymology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303690/
https://ncbi.nlm.nih.gov/pubmed/25433341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.588798
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados