Insights into the Role of the Unusual Disulfide Bond in Copper-Zinc Superoxide Dismutase

The functional and structural significance of the intrasubunit disulfide bond in copper-zinc superoxide dismutase (SOD1) was studied by characterizing mutant forms of human SOD1 (hSOD) and yeast SOD1 lacking the disulfide bond. We determined x-ray crystal structures of metal-bound and metal-deficien...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Sea, Kevin, Sohn, Se Hui, Durazo, Armando, Sheng, Yuewei, Shaw, Bryan F., Cao, Xiaohang, Taylor, Alexander B., Whitson, Lisa J., Holloway, Stephen P., Hart, P. John, Cabelli, Diane E., Gralla, Edith Butler, Valentine, Joan Selverstone
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2015
Konular:
Enzymology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303690/
https://ncbi.nlm.nih.gov/pubmed/25433341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.588798
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