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Neuroprotection by cyclodextrin in cell and mouse models of Alzheimer disease
There is extensive evidence that cholesterol and membrane lipids play a key role in Alzheimer disease (AD) pathogenesis. Cyclodextrins (CD) are cyclic oligosaccharide compounds widely used to bind cholesterol. Because CD exerts significant beneficial effects in Niemann-Pick type C disease, which sha...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3526350/ https://ncbi.nlm.nih.gov/pubmed/23209315 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20121239 |
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