Coenzyme Q10 Decreases Amyloid Pathology and Improves Behavior in a Transgenic Mouse Model of Alzheimer’s Disease

Increased oxidative stress is implicated in the pathogenesis of Alzheimer’s disease (AD). A large body of evidence suggests that mitochondrial dysfunction and increased reactive oxygen species occur prior to amyloid-β (Aβ) deposition. Coenzyme Q10 (CoQ10), a component of the mitochondrial electron t...

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Detalhes bibliográficos
Main Authors: Dumont, Magali, Kipiani, Khatuna, Yu, Fangmin, Wille, Elizabeth, Katz, Maya, Calingasan, Noel Y., Gouras, Gunnar K., Lin, Michael T., Beal, M. Flint
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3267988/
https://ncbi.nlm.nih.gov/pubmed/21799249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2011-110209
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