Triterpenoid CDDO–methylamide improves memory and decreases amyloid plaques in a transgenic mouse model of Alzheimer’s disease

Oxidative stress is one of the earliest events in the pathogenesis of Alzheimer’s disease (AD) and can markedly exacerbate amyloid pathology. Modulation of antioxidant and anti-inflammatory pathways represents an important approach for AD therapy. Synthetic triterpenoids have been found to facilitat...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Dumont, Magali, Wille, Elizabeth, Calingasan, Noel Y., Tampellini, Davide, Williams, Charlotte, Gouras, Gunnar K., Liby, Karen, Sporn, Michael, Beal, M. Flint, Lin, Michael T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083825/
https://ncbi.nlm.nih.gov/pubmed/19200343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2009.05970.x
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi