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Sequence-specific cleavage of the RNA strand in DNA–RNA hybrids by the fusion of ribonuclease H with a zinc finger

Ribonucleases (RNases) are valuable tools applied in the analysis of RNA sequence, structure and function. Their substrate specificity is limited to recognition of single bases or distinct secondary structures in the substrate. Currently, there are no RNases available for purely sequence-dependent f...

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Bibliografische gegevens
Hoofdauteurs: Sulej, Agata A., Tuszynska, Irina, Skowronek, Krzysztof J., Nowotny, Marcin, Bujnicki, Janusz M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526281/
https://ncbi.nlm.nih.gov/pubmed/23042681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks885
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