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Sequence-specific cleavage of the RNA strand in DNA–RNA hybrids by the fusion of ribonuclease H with a zinc finger

Ribonucleases (RNases) are valuable tools applied in the analysis of RNA sequence, structure and function. Their substrate specificity is limited to recognition of single bases or distinct secondary structures in the substrate. Currently, there are no RNases available for purely sequence-dependent f...

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Detaylı Bibliyografya
Asıl Yazarlar: Sulej, Agata A., Tuszynska, Irina, Skowronek, Krzysztof J., Nowotny, Marcin, Bujnicki, Janusz M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526281/
https://ncbi.nlm.nih.gov/pubmed/23042681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks885
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