Knockdown of Cathepsin B and uPAR Inhibits CD151 and α3β1 Integrin-mediated Cell Adhesion and Invasion in Glioma

Glioma is a highly complex brain tumor characterized by the dysregulation of proteins and genes that leads to tumor metastasis. Cathepsin B and uPAR are overexpressed in gliomas and they are postulated to play central roles in glioma metastasis. In this study, efficient downregulation of cathepsin B...

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Bibliographic Details
Main Authors: Malla, Rama Rao, Gopinath, Sreelatha, Alapati, Kiranmai, Gorantla, Bharathi, Gondi, Christopher S., Rao, Jasti S.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525767/
https://ncbi.nlm.nih.gov/pubmed/22495828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.21915
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