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uPAR and cathepsin B inhibition enhanced radiation-induced apoptosis in gliomainitiating cells

Glioblastomas present as diffuse tumors with invasion into normal brain tissue and frequently recur or progress after radiation as focal masses because of glioma-initiating cells. The role of the urokinase-type plasminogen activator receptor (uPAR) and cathepsin B in stem-like phenotype has been ext...

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Detalhes bibliográficos
Main Authors: Malla, Rama Rao, Gopinath, Sreelatha, Alapati, Kiranmai, Gorantla, Bharathi, Gondi, Christopher S., Rao, Jasti S.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367854/
https://ncbi.nlm.nih.gov/pubmed/22573309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nos088
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