Cathepsin B and uPAR Knockdown Inhibits Tumor-induced Angiogenesis by Modulating VEGF Expression in Glioma

Angiogenesis, which is the process of sprouting of new blood vessels from pre-existing vessels, is vital for tumor progression. Proteolytic remodeling of extracellular matrix is a key event in vessel sprouting during angiogenesis. Urokinase plasminogen activator receptor (uPAR) and cathepsin B are b...

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Hauptverfasser: Malla, Rama Rao, Gopinath, Sreelatha, Gondi, Christopher S., Alapati, Kiranmai, Dinh, Dzung H., Gujrati, Meena, Rao, Jasti S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096680/
https://ncbi.nlm.nih.gov/pubmed/21394106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2011.9
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