Long-Term Engraftment of Human Natural T Regulatory Cells in NOD/SCID IL2rγc(null) Mice by Expression of Human IL-2

Regulatory T cells are essential to maintain immune homeostasis and prevent autoimmunity. Therapy with in vitro expanded human nT(Regs) is being tested to prevent graft versus host disease, which is a major cause for morbidity and mortality associated with hematopoietic stem cell transplantation. Th...

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Autors principals: Abraham, Sojan, Pahwa, Rajendra, Ye, Chunting, Choi, Jang-gi, Pahwa, Savita, Jaggaiahgari, Shashidhar, Raut, Ashwin, Chen, Shuiping, Manjunath, N., Shankar, Premlata
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525660/
https://ncbi.nlm.nih.gov/pubmed/23272176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051832
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