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Regulation of Mcl-1 by SRSF1 and SRSF5 in Cancer Cells

Up-regulation of the apoptosis-regulatory gene Mcl-1 (myeloid cell leukemia-1) occurs in different cancer types and is linked with drug resistance to cancer therapies. It is well known that Mcl-1 pre-mRNA undergoes alternative splicing events to produce two functionally distinct proteins, Mcl-1(S) (...

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Bibliografski detalji
Glavni autori: Gautrey, Hannah L., Tyson-Capper, Alison J.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3524227/
https://ncbi.nlm.nih.gov/pubmed/23284704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051497
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