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Loss of Atrx Sensitizes Cells to DNA Damaging Agents through p53-Mediated Death Pathways
Prevalent cell death in forebrain- and Sertoli cell-specific Atrx knockout mice suggest that Atrx is important for cell survival. However, conditional ablation in other tissues is not associated with increased death indicating that diverse cell types respond differently to the loss of this chromatin...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3524112/ https://ncbi.nlm.nih.gov/pubmed/23284920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052167 |
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