Compromised genomic integrity impedes muscle growth after Atrx inactivation

ATR-X syndrome is a severe intellectual disability disorder caused by mutations in the ATRX gene. Many ancillary clinical features are attributed to CNS deficiencies, yet most patients have muscle hypotonia, delayed ambulation, or kyphosis, pointing to an underlying skeletal muscle defect. Here, we...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Huh, Michael S., Price O’Dea, Tina, Ouazia, Dahmane, McKay, Bruce C., Parise, Gianni, Parks, Robin J., Rudnicki, Michael A., Picketts, David J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2012
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533543/
https://ncbi.nlm.nih.gov/pubmed/23114596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI63765
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