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Loss of Atrx Sensitizes Cells to DNA Damaging Agents through p53-Mediated Death Pathways
Prevalent cell death in forebrain- and Sertoli cell-specific Atrx knockout mice suggest that Atrx is important for cell survival. However, conditional ablation in other tissues is not associated with increased death indicating that diverse cell types respond differently to the loss of this chromatin...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3524112/ https://ncbi.nlm.nih.gov/pubmed/23284920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052167 |
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