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Loss of Atrx Sensitizes Cells to DNA Damaging Agents through p53-Mediated Death Pathways

Prevalent cell death in forebrain- and Sertoli cell-specific Atrx knockout mice suggest that Atrx is important for cell survival. However, conditional ablation in other tissues is not associated with increased death indicating that diverse cell types respond differently to the loss of this chromatin...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Conte, Damiano, Huh, Michael, Goodall, Emma, Delorme, Marilyne, Parks, Robin J., Picketts, David J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3524112/
https://ncbi.nlm.nih.gov/pubmed/23284920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052167
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