Stalled replication forks within heterochromatin require ATRX for protection

Expansive growth of neural progenitor cells (NPCs) is a prerequisite to the temporal waves of neuronal differentiation that generate the six-layered neocortex, while also placing a heavy burden on proteins that regulate chromatin packaging and genome integrity. This problem is further reflected by t...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Huh, M S, Ivanochko, D, Hashem, L E, Curtin, M, Delorme, M, Goodall, E, Yan, K, Picketts, D J
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4917659/
https://ncbi.nlm.nih.gov/pubmed/27171262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.121
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