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Recovery from impaired muscle growth arises from prolonged postnatal accretion of myonuclei in Atrx mutant mice

Reduced muscle mass due to pathological development can occur through several mechanisms, including the loss or reduced proliferation of muscle stem cells. Muscle-specific ablation of the α-thalassemia mental retardation syndrome mutant protein, Atrx, in transgenic mice results in animals with a sev...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Huh, Michael S., Young, Kevin G., Yan, Keqin, Price-O’Dea, Tina, Picketts, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5667798/
https://ncbi.nlm.nih.gov/pubmed/29095838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186989
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