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Chemogenomic approach identified yeast YLR143W as diphthamide synthetase

Many genes are of unknown functions in any sequenced genome. A combination of chemical and genetic perturbations has been used to investigate gene functions. Here we present a case that such “chemogenomics” information can be effectively used to identify missing genes in a defined biological pathway...

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Bibliografiset tiedot
Päätekijät: Su, Xiaoyang, Lin, Zhewang, Chen, Wei, Jiang, Hong, Zhang, Sheng, Lin, Hening
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3523822/
https://ncbi.nlm.nih.gov/pubmed/23169644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1214346109
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