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Chemogenomic approach identified yeast YLR143W as diphthamide synthetase
Many genes are of unknown functions in any sequenced genome. A combination of chemical and genetic perturbations has been used to investigate gene functions. Here we present a case that such “chemogenomics” information can be effectively used to identify missing genes in a defined biological pathway...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3523822/ https://ncbi.nlm.nih.gov/pubmed/23169644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1214346109 |
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