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Dph7 Catalyzes a Previously Unknown Demethylation Step in Diphthamide Biosynthesis

[Image: see text] Present on archaeal and eukaryotic translation elongation factor 2, diphthamide represents one of the most intriguing post-translational modifications on proteins. The biosynthesis of diphthamide was proposed to occur in three steps requiring seven proteins, Dph1–7, in eukaryotes....

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Detalhes bibliográficos
Main Authors: Lin, Zhewang, Su, Xiaoyang, Chen, Wei, Ci, Bo, Zhang, Sheng, Lin, Hening
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015618/
https://ncbi.nlm.nih.gov/pubmed/24739148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja5009272
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