Probing multidrug-resistance/protein-ligand interaction with oxatricyclic designed ligands in HIV-1 Protease inhibitors

Samankaltaisia teoksia

• GRL-0519, a Novel Oxatricyclic Ligand-Containing Nonpeptidic HIV-1 Protease Inhibitor (PI), Potently Suppresses Replication of a Wide Spectrum of Multi-PI-Resistant HIV-1 Variants In Vitro
  Tekijä: Amano, Masayuki, et al.
  Julkaistu: (2013)
• Design and Synthesis of Highly Potent HIV-1 Protease Inhibitors Containing Tricyclic Fused Ring Systems as Novel P2-ligands: Structure-Activity Studies, Biological and X-ray Structural Analysis
  Tekijä: Ghosh, Arun K., et al.
  Julkaistu: (2018)
• Design and Development of Highly Potent HIV-1 Protease Inhibitors with a Crown-like Oxotricyclic Core as the P2-Ligand to Combat Multidrug-Resistant HIV Variants
  Tekijä: Ghosh, Arun K., et al.
  Julkaistu: (2017)
• Design, Synthesis, Biological Evaluation, and X-ray Studies of HIV-1 Protease Inhibitors with Modified P2′ Ligands of Darunavir
  Tekijä: Ghosh, Arun K., et al.
  Julkaistu: (2017)
• Structure-Based Design of Highly Potent HIV-1 Protease Inhibitors Containing New Tricyclic Ring P2-Ligands: Design, Synthesis, Biological, and X-ray Structural Studies
  Tekijä: Ghosh, Arun K., et al.
  Julkaistu: (2020)