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Pharmacology of Cefaclor in Normal Volunteers and Patients with Renal Failure
After a 500-mg dose of cefaclor, the mean peak plasma level was 12.4 μg/ml and after a 250-mg dose it was 5 μg/ml in normal volunteers. Food intake significantly reduced absorption. Probenecid prolonged plasma levels. Mean plasma half-life in normal volunteers was 0.8 h. Only about 50% of the dose w...
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| Udgivet i: | Antimicrob Agents Chemother |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
1978
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352368/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/677862/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.13.6.951 |
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