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Pharmacokinetics of Cefaclor and Cephalexin: Dosage Nomograms for Impaired Renal Function

The pharmacokinetics of cefaclor and cephalexin were characterized in patients with creatinine clearances ranging from 0 to 147 ml/min. Each of 24 fasted subjects received a single 500-mg oral dose of cefaclor, and 13 of these subjects later received 500 mg of cephalexin. Serum and urine levels of t...

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Bibliographische Detailangaben
Hauptverfasser: Spyker, Daniel A., Thomas, Bruce L., Sande, Merle A., Bolton, W. Kline
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1978
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC352429/
https://ncbi.nlm.nih.gov/pubmed/697345
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