Pharmacokinetics of Cefaclor and Cephalexin: Dosage Nomograms for Impaired Renal Function

The pharmacokinetics of cefaclor and cephalexin were characterized in patients with creatinine clearances ranging from 0 to 147 ml/min. Each of 24 fasted subjects received a single 500-mg oral dose of cefaclor, and 13 of these subjects later received 500 mg of cephalexin. Serum and urine levels of t...

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Bibliographic Details

Published in:	Antimicrob Agents Chemother
Main Authors:	Spyker, Daniel A., Thomas, Bruce L., Sande, Merle A., Bolton, W. Kline
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 1978
Subjects:	Pharmacology and Therapeutics
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352429/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/697345/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.14.2.172
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