Pharmacokinetics of Cefaclor in Patients with End Stage Renal Disease and During Hemodialysis

A single 1.0-g dose of cefaclor administered to patients with stable end stage renal disease whose creatinine clearances were <5 ml/min produced a mean peak serum concentration of 48.3 ± 19.8 μg/ml. The half-life was 2.3 ± 0.3 h. Hemodialysis shortened the half-life of a similar dose to 1.6 ± 0.3...

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Hlavní autoři: Berman, S. J., Boughton, W. H., Sugihara, J. G., Wong, E. G. C., Sato, M. M., Siemsen, A. W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 1978
Témata:
Pharmacology and Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC352452/
https://ncbi.nlm.nih.gov/pubmed/708006
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