Insulin Resistance, Ceramide Accumulation and Endoplasmic Reticulum Stress in Experimental Chronic Alcohol-Induced Steatohepatitis

Aims: Chronic alcohol abuse causes steatohepatitis with insulin resistance, which impairs hepatocellular growth, survival and metabolism. However, growing evidence supports the concept that progressive alcohol-related liver injury may be mediated by concurrent mal-signaling through other networks th...

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Главные авторы: Ramirez, Teresa, Longato, Lisa, Dostalek, Miroslav, Tong, Ming, Wands, Jack R., de la Monte, Suzanne M.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2013
Предметы:
Pharmacology and Cell Metabolism
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3523384/
https://ncbi.nlm.nih.gov/pubmed/22997409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/alcalc/ags106
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