Insulin Resistance, Ceramide Accumulation, and Endoplasmic Reticulum Stress in Human Chronic Alcohol-Related Liver Disease

Background. Chronic alcohol-related liver disease (ALD) is mediated by insulin resistance, mitochondrial dysfunction, inflammation, oxidative stress, and DNA damage. Recent studies suggest that dysregulated lipid metabolism with accumulation of ceramides, together with ER stress potentiate hepatic...

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Detaylı Bibliyografya
Asıl Yazarlar: Lisa Longato, Kelsey Ripp, Mashiko Setshedi, Miroslav Dostalek, Fatemeh Akhlaghi, Mark Branda, Jack R. Wands, Suzanne M. de la Monte
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Hindawi Limited 2012-01-01
Seri Bilgileri:Oxidative Medicine and Cellular Longevity
Online Erişim:http://dx.doi.org/10.1155/2012/479348
Etiketler: Etiketle
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