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Ceramide-Mediated Insulin Resistance and Impairment of Cognitive-Motor Functions

Obesity, type 2 diabetes mellitus (T2DM), and non-alcoholic steatohepatitis (NASH) are associated with cognitive impairment, brain insulin resistance, and neurodegeneration. Recent studies linked these effects to increased pro-ceramide gene expression in liver and increased ceramide levels in serum....

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Hlavní autoři: de la Monte, Suzanne M., Tong, Ming, Nguyen, VanAnh, Setshedi, Mashiko, Longato, Lisa, Wands, Jack R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952443/
https://ncbi.nlm.nih.gov/pubmed/20693650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2010-091726
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