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Insulin resistance and neurodegeneration: Roles of obesity, type 2 diabetes mellitus and non-alcoholic steatohepatitis

Recent studies have linked obesity, type 2 diabetes mellitus (T2DM) or non-alcoholic steatohepatitis (NASH) to insulin resistance in the brain, cognitive impairment and neurodegeneration. Insulin resistance compromises cell survival, metabolism and neuronal plasticity, and increases oxidative stress...

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Detalhes bibliográficos
Publicado no:Curr Opin Investig Drugs
Main Authors: de la Monte, Suzanne M, Longato, Lisa, Tong, Ming, Wands, Jack R
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600072/
https://ncbi.nlm.nih.gov/pubmed/19777393
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