Insulin and Insulin-Like Growth Factor Resistance in Alcoholic Neurodegeneration

BACKGROUND: Chronic alcohol feeding of adult Long Evans rats causes major central nervous system abnormalities that link neuronal loss and impaired acetylcholine homeostasis to ethanol inhibition of insulin and insulin-like growth factor (IGF) signaling and increased oxidative stress. OBJECTIVES: We...

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Hauptverfasser: de la Monte, Suzanne M., Tong, Ming, Cohen, Ariel C., Sheedy, Donna, Harper, Clive, Wands, Jack R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3391554/
https://ncbi.nlm.nih.gov/pubmed/18616667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1530-0277.2008.00731.x
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