6,7-Dihydroxy-1-oxoisoindoline-4-sulfonamide-containing HIV-1 Integrase Inhibitors

Although an extensive body of scientific and patent literature exists describing the development of HIV-1 integrase (IN) inhibitors, Merck’s raltegravir and Gilead’s elvitegravir remain the only IN inhibitors FDA-approved for the treatment of AIDS. The emergence of raltegravir-resistant strains of H...

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Bibliographic Details
Main Authors:	Zhao, Xue Zhi, Maddali, Kasthuraiah, Smith, Steven J., Métifiot, Mathieu, Johnson, Barry C., Marchand, Christophe, Hughes, Stephen H., Pommier, Yves, Burke, Terrence R.
Format:	Artigo
Language:	Inglês
Published:	2012
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3523327/ https://ncbi.nlm.nih.gov/pubmed/23149229 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2012.10.088
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6,7-Dihydroxy-1-oxoisoindoline-4-sulfonamide-containing HIV-1 Integrase Inhibitors

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