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An Early-Age Increase in Vacuolar pH Limits Mitochondrial Function and Lifespan in Yeast
Mitochondria play a central role in ageing. They are considered to be both a target of the ageing process, as well as a contributor to it(1). Alterations in mitochondrial structure and function are evident during ageing in most eukaryotes(2), but how this occurs is poorly understood. Here, we identi...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3521838/ https://ncbi.nlm.nih.gov/pubmed/23172144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11654 |
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