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An Early-Age Increase in Vacuolar pH Limits Mitochondrial Function and Lifespan in Yeast

Mitochondria play a central role in ageing. They are considered to be both a target of the ageing process, as well as a contributor to it(1). Alterations in mitochondrial structure and function are evident during ageing in most eukaryotes(2), but how this occurs is poorly understood. Here, we identi...

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Detaylı Bibliyografya
Asıl Yazarlar: Hughes, Adam L., Gottschling, Daniel E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3521838/
https://ncbi.nlm.nih.gov/pubmed/23172144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11654
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