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pH neutralization protects against reduction in replicative lifespan following chronological aging in yeast

Chronological and replicative aging have been studied in yeast as alternative paradigms for post-mitotic and mitotic aging, respectively. It has been known for more than a decade that cells of the S288C background aged chronologically in rich medium have reduced replicative lifespan relative to chro...

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Detalhes bibliográficos
Main Authors: Murakami, Christopher, Delaney, Joe R., Chou, Annie, Carr, Daniel, Schleit, Jennifer, Sutphin, George L., An, Elroy H., Castanza, Anthony S., Fletcher, Marissa, Goswami, Sarani, Higgins, Sean, Holmberg, Mollie, Hui, Jessica, Jelic, Monika, Jeong, Ki-Soo, Kim, Jin R., Klum, Shannon, Liao, Eric, Lin, Michael S., Lo, Winston, Miller, Hillary, Moller, Richard, Peng, Zhao J., Pollard, Tom, Pradeep, Prarthana, Pruett, Dillon, Rai, Dilreet, Ros, Vanessa, Schuster, Alex, Singh, Minnie, Spector, Benjamin L., Vander Wende, Helen, Wang, Adrienne M., Wasko, Brian M., Olsen, Brady, Kaeberlein, Matt
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442919/
https://ncbi.nlm.nih.gov/pubmed/22871733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.21465
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