Molecular mechanisms underlying genotype-dependent responses to dietary restriction

Dietary restriction (DR) increases lifespan and attenuates age-related phenotypes in many organisms; however, the effect of DR on longevity of individuals in genetically heterogeneous populations is not well characterized. Here we describe a large-scale effort to define molecular mechanisms that und...

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Auteurs principaux: Schleit, Jennifer, Johnson, Simon C., Bennett, Christopher F., Simko, Marissa, Trongtham, Natalie, Castanza, Anthony, Hsieh, Edward J., Moller, Richard M., Wasko, Brian M., Delaney, Joe R., Sutphin, George L., Carr, Daniel, Murakami, Christopher J., Tocchi, Autumn, Xian, Bo, Chen, Weiyang, Yu, Tao, Goswami, Sarani, Higgins, Sean, Holmberg, Mollie, Jeong, Ki-Soo, Kim, Jin R., Klum, Shannon, Liao, Eric, Lin, Michael S., Lo, Winston, Miller, Hillary, Olsen, Brady, Peng, Zhao J., Pollard, Tom, Pradeep, Prarthana, Pruett, Dillon, Rai, Dilreet, Ros, Vanessa, Singh, Minnie, Spector, Benjamin L., Wende, Helen Vander, An, Elroy H., Fletcher, Marissa, Jelic, Monika, Rabinovitch, Peter S., MacCoss, Michael J., Han, Jing-Dong J., Kennedy, Brian K., Kaeberlein, Matt
Format: Artigo
Langue:Inglês
Publié: 2013
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838465/
https://ncbi.nlm.nih.gov/pubmed/23837470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12130
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