Molecular mechanisms underlying genotype-dependent responses to dietary restriction

Dietary restriction (DR) increases lifespan and attenuates age-related phenotypes in many organisms; however, the effect of DR on longevity of individuals in genetically heterogeneous populations is not well characterized. Here we describe a large-scale effort to define molecular mechanisms that und...

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Главные авторы: Schleit, Jennifer, Johnson, Simon C., Bennett, Christopher F., Simko, Marissa, Trongtham, Natalie, Castanza, Anthony, Hsieh, Edward J., Moller, Richard M., Wasko, Brian M., Delaney, Joe R., Sutphin, George L., Carr, Daniel, Murakami, Christopher J., Tocchi, Autumn, Xian, Bo, Chen, Weiyang, Yu, Tao, Goswami, Sarani, Higgins, Sean, Holmberg, Mollie, Jeong, Ki-Soo, Kim, Jin R., Klum, Shannon, Liao, Eric, Lin, Michael S., Lo, Winston, Miller, Hillary, Olsen, Brady, Peng, Zhao J., Pollard, Tom, Pradeep, Prarthana, Pruett, Dillon, Rai, Dilreet, Ros, Vanessa, Singh, Minnie, Spector, Benjamin L., Wende, Helen Vander, An, Elroy H., Fletcher, Marissa, Jelic, Monika, Rabinovitch, Peter S., MacCoss, Michael J., Han, Jing-Dong J., Kennedy, Brian K., Kaeberlein, Matt
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838465/
https://ncbi.nlm.nih.gov/pubmed/23837470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12130
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