Metabolic Fate of [(14)C]Cefamandole, a Parenteral Cephalosporin Antibiotic, in Rats and Dogs

The biotransformation of the parenterally effective cephalosporin antibiotic cefamandole nafate (I) has been studied in rats and dogs. After rapid in vivo hydrolysis of the nafate pharmaceutical form to cefamandole (II), the antibiotic was found to be very resistant to metabolic degradation in both...

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Bibliografske podrobnosti

izdano v:	Antimicrob Agents Chemother
Principais autores:	Sullivan, H. R., Due, S. L., Kau, D. L. K., Quay, J. F., Miller, W. M.
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 1977
Teme:	Pharmacology and Therapeutics
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352156/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/883820/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.12.1.73
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