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Metabolic Fate of [(14)C]Cefamandole, a Parenteral Cephalosporin Antibiotic, in Rats and Dogs
The biotransformation of the parenterally effective cephalosporin antibiotic cefamandole nafate (I) has been studied in rats and dogs. After rapid in vivo hydrolysis of the nafate pharmaceutical form to cefamandole (II), the antibiotic was found to be very resistant to metabolic degradation in both...
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| Publicado no: | Antimicrob Agents Chemother |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1977
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352156/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/883820/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.12.1.73 |
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