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Metabolic Fate of [(14)C]Cefamandole, a Parenteral Cephalosporin Antibiotic, in Rats and Dogs

The biotransformation of the parenterally effective cephalosporin antibiotic cefamandole nafate (I) has been studied in rats and dogs. After rapid in vivo hydrolysis of the nafate pharmaceutical form to cefamandole (II), the antibiotic was found to be very resistant to metabolic degradation in both...

詳細記述

保存先:
書誌詳細
主要な著者: Sullivan, H. R., Due, S. L., Kau, D. L. K., Quay, J. F., Miller, W. M.
フォーマット: Artigo
言語:Inglês
出版事項: 1977
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC352156/
https://ncbi.nlm.nih.gov/pubmed/883820
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