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Antitussive effects of the peripherally restricted GABA(B) receptor agonist lesogaberan in guinea pigs: comparison to baclofen and other GABA(B) receptor-selective agonists
BACKGROUND: Gastroesophageal reflux disease (GERD) is a common cause of chronic cough. Both acid and nonacid reflux is thought to play a role in the initiation of coughing and cough hypersensitivity. The GABA(B) receptor agonist lesogaberan was developed as a peripherally restricted anti-reflux ther...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3520872/ https://ncbi.nlm.nih.gov/pubmed/23025757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-9974-8-7 |
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