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Antitussive activity of sigma-1 receptor agonists in the guinea-pig
1. Current antitussive medications have limited efficacy and often contain the opiate-like agent dextromethorphan (DEX). The mechanism whereby DEX inhibits cough is ill defined. DEX displays affinity at both NMDA and sigma receptors, suggesting that the antitussive activity may involve central or pe...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1574192/ https://ncbi.nlm.nih.gov/pubmed/14691051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705605 |
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